Relevant biological questions

• Analyses of enzyme mechanisms

• Comparative studies of enzymes from different organisms

• Coupling between electron transfer and proton translocation

• Protonation state of specific residues and cofactors

• Conformational changes ocurring upon redox reaction or temperature increase

• Protein / protein, protein / lipids, protéine / métals interactions

Studied proteins

• Membrane proteins from the respiratory chain (NADH-ubiquinone oxydoreductase or complex I, succinate-ubiquinone oxydoreductase or complex II, ubiquinol-cytochrome c oxydoreductase or complex III, cytochrome c oxidase or complex IV)

• Adrenodoxin / Adrenodoxin reductase

• Hemocyanin

• β-Amyloïds