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Publications

2024

"Enhancing affinity purification of monoclonal antibodies from human serum for subsequent CZE-MS analysis"

T. Reinert, P. Houzé, YN Francois, R. Gahoual Journal of Chromatography B, 2024, 123974 (pdf)

2023

"High levels of polycyclic aromatic compounds in outdoor and indoor PM10 of an urban residential environment during a winter pollution event in Strasbourg, France"

M. Galmiche, O. Delhomme, S. le Calvé, YN. Francois, M. Millet, Air Quality, Atmosphere & Health, 2023, Accepted (pdf)


"Post-translational modifications comparative identification and kinetic study of infliximab innovator and biosimilars in serum using capillary electrophoresis-tandem mass spectrometry"

T. Reinert, P. Houzé, N. Mignet, YN Francois, R. Gahoual Journal of Pharmaceutical and Biomedical Analysis, 2023, 234, 115541 (pdf)


"Simultaneous quantification and structural characterization of monoclonal antibodies after administration using capillary zone electrophoresis-tandem mass spectrometry"

T. Reinert, R. Gahoual, N. Mignet, A. Kulus, M. Allez, P. Houzé, YN Francois, Journal of Pharmaceutical and Biomedical Analysis, 2023, 233, 115446 (pdf)


"Method development for the LC-MS/MS determination of C60 and C70 fullerenes and their functionalized derivatives in airborne particulate matter, settled dust and soot"

M. Galmiche, E. Esslinger, O. Delhomme, P. Schaeffer, E. Motsch,  E. Leize-Wagner, YN. Francois, M. Millet, International Journal of Mass Spectrometry, 2023, 490, 117072 (pdf)


"Hyphenation of Fourier Transform Iop, Cyclotron Resonance Mass Specrometry (FT-ICR MS) with separation methods: the art of compromises and the possible"

C. Gosset-Erard, F. Aubriet, E. Leize-Wagner, YN. Francois, P. Chaimbault, Talanta, 2023, 257, 124324 (pdf)


"Nucleos'ID: new search engine enabling the untargeted identification of RNA post-transcriptional modifications from tandem mass spectrometry analyses of nucleosides""

C. Gosset-Erard, M. Didierjean, J. Pansanel, A. Lechner, P. Wolff, L. Kuhn, F. Aubriet, E. Leize-Wagner, P. Chaimbault, YN. Francois, Analytical Chemistry, 2023, 95, 2, 1608-1617 (pdf)

2022

"Simultaneous Determination of 79 Polar and Non-Polar Polycyclic Aromatic Compounds in Airborne Particulate Matter by Gas Chromatography-tandem Mass Spectrometry"

M. Galmiche, A. Sonnette, M. Wolf, C. Sutter, O. Delhomme, YN Francois, M. Millet, Polycyclic Aromatic Compounds, 2022, In press (pdf)


Book Chapter "CE-MS methods for the characterization of monoclonal antibodies" in Capillary Electrophoresis Mass Spectrometry for Proteomics and Metabolomics : Principles and Applications

T. Reinert, A. Beck, P. Houzé, R. Gahoual, YN. Francois, edited by R. Ramautar and D. Chen, 2022, ISBN: 978-3-527-34921-0 (pdf)



"Optimization of nucleotides dephosphorylation for RNA structural characterization by tandem mass spectrometry hyphenated with separation methods"

C. Gosset-Erard, A. Lechner, P. Wolff, F. Aubriet, E. Leize-Wagner, P. Chaimbault, YN Francois, Journal of Chromatography B, 2022, 1208, 123396 (pdf)


Book Chapter "Protocol for Etching Bare-Fused Silic Capillaries for Sheathless Capillary Electrophoresis-Mass Spectrometry Coupling" in Methods in Molecular Biology: Mass Spectrometry of Glycoprotein

C. Gosset-Errard, J. Giorgetti, M. Biacchi, F. Aubriet, E. Leize-Wagner, P. Chaimbault, YN. Francois, edited by C. Neusüss, K. Jooss, 2022, vol 2531, 49-59 (pdf)


"The use of pseudo-MRM for a sensitive and selective detection and quantification of polycyclic aromatic compounds by tandem mass spectrometry"

M. Galmiche, A. Rodrigues, E. Motsch, O. Delhomme, YN. Francois, M. Millet, Rapid Communications in Mass Spectrometry, 2022, 36, e9307 (pdf)

2021

"CEToolbox: Specialized Calculator for Capillary Electrophoresis Users as an Android Application"

YN. Francois, M. Biacchi, R. Gahoual, A. Vezin, J. Pansanel, Electrophoresis, 2021, Accepted (pdf)


Book Chapter "Analytsis of Monoclonal Antibody Glycopeptides by Capillary Electrophoresis-Mass Spectrometry Coupling" in Methods in Molecular Biology: Mass Spectrometry of Glycoprotein

J. Saadé, M. Biacchi, J. Giorgetti, A. Lechner, A. Beck, E. Leize-Wagner, Y.N. Francois, edited by A. Delobel,  Springer, 2021 (pdf)


Book Chapter "Fast Afucosylation Profiling of Glycoengineered Antibody Subunits by Middle-Up Mass Spectrometry" in Methods in Molecular Biology: Mass Spectrometry of Glycoprotein"

E. Wagner-Rousset, O. Colas, S. Chenu, Y.N. Francois, D. Guillarme, S. Cianferani, Y.O. Tsybin, J. Sjögren, A. Delobel, A. Beck, edited by A. Delobel,  Springer, 2021 (pdf)


"Characterization of hydrocarbon detradation, biosurfactant production, and biofilm formation in Serratia sp. Tan611 : a new strain isolated from industrially contaminated environment in Algeria"

A. Semai, F. Plewniak, A. Charrié-Duhaut, A. Sayeh, C. Vandecasteele, C. Lopez-Roques, E. Leize-Wagner, F. Bensalah, P. Bertin, Antonie van Leeuwenhoek, 2021, 114, 411-424 (pdf)


"Les restes organiques minéralisés : un nouveau champ d'investigation en contexte funéraire. Exemple de la nécropole de Merxheim "Obere Reben" (Haut-Rhin).

A. Charrié-Duhaut, F. Médard, C. Proust, H. Barrand-Emam, dans C. Carpentier, R.-M. Arbogast & Ph. Kuchler (dir.), Bioarchéologie : minimums méthodologiques, référentiels communs et nouvelles approches : actes du 4e séminaire scientifique et technique de l’Inrap, 28-29 nov. 2019, Sélestat. <https://doi.org/10.34692/ftgf-zd86>.


"Simultaneous determination of 80 polar and non-polar Polycyclic Aromatic Compounds in airborne PM and settled dust by GC-MS/MS"

M. Galmiche, O. Delhomme, A. Sonnette, V. Duflot, YN. François, M. Millet, Proceedings of the 69th ASMS Conference on Mass Spectrometry and Allied Topics, 2021


“Characterization of post-transcriptional RNA modifications by capillary electrophoresis - high resolution mass spectrometry”

Gosset-Erard C., Lechner A., Wolff P., Leize-Wagner E., Aubriet F., Francois Y.-N., Chaimbault P., Proceedings of the 69th ASMS Conference on Mass Spectrometry and Allied Topics, 2021


"Environmental analysis of polar and non-polar Polycyclic Aromatic Compounds in airborne particulate matter, sttled dust and soot: Part II: Instrumental analysis and occurence"

M. Galmiche, O. Delhomme, Y.N. Francois, M. Millet, TrAC Trends in Analytical Chemistry, 2021, 134, 116146  (pdf)


"Environmental analysis of polar and non-polar Polycyclic Aromatic Compounds in airborne particulate matter, sttled dust and soot: Part I: Sampling and sample preparation"

M. Galmiche, O. Delhomme, Y.N. Francois, M. Millet, TrAC Trends in Analytical Chemistry, 2021, 134, 116099 (pdf)


2020

"Capillary electrophoresis-Mass spectrometry at Trial by Metabo-ring: Effective electrophoretic mobility for Reproducible and Robust Compound Annotation"

N. Drouin,[19 auteurs], Y-N. Francois, A. Lechner,[23 auteurs], S. Rudaz, R. Ramautar, Analytical Chemistry, 2020, 92, 20, 14103–14112, (pdf)


"Bio-archéologie: Sensibilisation au prélèvement, au stockage et à l'étude de macro/micro-résidus organiques"

A. Charrié-Duhaut, R. Fédard, A. Mazuy, Zenodo, 2020 (pdf)


"Aggregation and amyloidogenicity of nuclear coactivator binding domain of CREB-binding protein"

A.M. Garcia, G. Giorgiutti, Y. El Khoury, V. Bauer, C. Spiegelhalter, E. Leize-Wagner, P. Hellwig, N. Potier, V. Torbeev, Chemistry A European Journal, 2020, 44, 9889-9899 (pdf)


"Characterization of post-transcriptional RNA modifications by sheathless capillary electrophoresis - high resolution mass spectrometry"

A. Lechner, P. Wolff, A. Leize-Wagner, Y.N. Francois, Analytical Chemistry, 2020, 92, 10, 7363–7370 (pdf)


Book Chapter "Emerging biotechnological approaches with respect to tissue regeneration: from improving biomaterial incorporation to comprehensive omics monitoring" in Biomaterials for Organ and Tissue Regeneration in Woodhead Publishing Series in Biomaterials

R. Gahoual, Y.N. Francois, N. Mignet, P. Houzé, edited by NH. Vrana, H. Knopf-Marques, J. Barthes, Elsevier, 2020 (pdf)


"Kinetic and structural characterization of therapeutic albumin chemical functionalization using complementary mass spectrometry techniques"

R. Gahoual*, G. Bolbach, I. Ould-Melha, G. Clodic, Y.-N. François, D. Scherman, N. Mignet, P. Houzé , Journal of Pharmaceutical and Biomedical Analysis, 2020,185, 113242 (pdf)


"Determination of size variants by CE-SDS for approved therapeutic antibodies: bey implications of subclasses and light chain specificitie"

V. D'Atri, E. Wagner-Rousset, O. Colas, S. Chenu, A. Goyon, A. Murisier, S. Cianferani, Y. Francois, S. Fekete, D. Guillarme, A. Beck, Journal of Pharmaceutical and Biomedical Analysis, 2020, 184, 113166 (pdf)

 

"Combination of intact, middle-up and bottom-up levels to characterize 7 therapeutic monoclonal antibodies by capillary electrophoresis - mass spectrometry"

J. Giorgetti, A. Beck, E. Leize-Wagner, YN. Francois. Journal of Pharmaceutical and Biomedical Analysis, 2020, 182, 113107 (pdf)

 

"Sur la piste des matériaux organiques grâce à la spectrométrie de masse"

A. Charrié-Duhaut, M. Leroy, S. Deffressigne. Dans les actes de la 7ème journée d’étude Corpus Métal et matériaux périssables de Strasbourg

 

"Les parures annulaires et en croissant en tôle d’alliage cuivreux du VIIe au IIIe s. av. J.-C. (Hallstatt D à la Tène B) : nature des remplissages en bois et techniques de fabrication (Bas-Rhin et Haut-Rhin)"

A. Mulot, M. Binggeli, A. Charrié-Duhaut, W. Tegel. Dans les actes de la 7ème journée d’étude Corpus Métal et matériaux périssables de Strasbourg

2019

"NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results frlm Diverse Analytical Methods"

M.L.A. De Leoz, D.L Duewer, [153 authors], N. Said, Y.N. Francois, E. Leize-Wagner, [9 authors], S.E. Stein, Molecular and Cellular Proteomics, 2019, 19, 11-30. (pdf)


Book Chapter "Drug loading and distribution of ADCs after reduction of IdeS digestion and reduction" in Methods in Molecular Biology: Antibody-Drug Conjugates: Methods and Protocols

E. Wagner-Rousset, O. Colas, Y.N. Francois, S. Heinish, D. Guillarme, S. Cianferan, A. Beck, edited by N. Tumey, Springer, 2019 (pdf)


Book Chapter "Characterization of the primary structure of cysteine-linked Antibody-Drug Conjugates using Capillary Electrophoresis with Mass Spectrometry" in Methods in Molecular Biology: Antibody-Drug Conjugates: Methods and Protocols

J. Saadé, R. Gahoual, A. Beck, E. Leize-Wagner, Y.N. Francois, edited by N. Tumey, Springer, 2019 (pdf)


"Revealing the potential of capillary electrophoresis-mass spectrometry: the tipping point"

R. Gahoual, E. Leize-Wagner, P. Houzé, YN François, Rapid Communications in Mass Spectrometry, 2018, 33,11-19 (pdf)


"The chemo- and stereoselective formation of Pallado- and Platinocryptophanes"

A. Schaly, M. Meyer, J.C. Chambron, M. Jean, N. Vanthuyne, E. Aubert, E. Espinosa, N. Zorn, E. Leize-Wagner European Journal of Inorganic Chemistry, 2019, 22, 2691-2706 (pdf)


"Insights from capillary electrophoresis approaches for characterization of monoclonal antibodies and antibody drug conjugates in the period 2016–2018"

A. Lechner, J. Giorgetti, R. Gahoual, A. Beck, E. Leize-Wagner, Y. Francois Journal of Chromatography B, 2019, 1122-1123, 1-17 (pdf)


Book Chapter "Capillary Electrophoresis Coupled to Mass Spectrometry as a Powerful Tool to Investigate Heterogeneities Conformers, and Oligomers of Intact Proteins" in Advances in Chromatography, Volume 56

Y.N. Francois, A.L. Marie, C. Ruel, R. Gahoual, N.T. Tran, M. Taverna, edited by N. Grinberg and P.W. Carr, CRC Press Taylor and Francis, 2019, 137-157 (pdf)


"Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: prensent and future"

A. Beck, V. D'Atri, A. Ehkirch, S. Fekete, O. Hernandez, R. Gahoual, E. Leize-Wagner, Y. Francois, D. Guillarme, S. Cianférani, Expert Review of Proteomics, 2019, 16,337-362 (pdf)

2018

"Les matériaux organiques dans les sépultures du haut moyen âge : état de la recherche et cas d’études provenant de la nécropole de Merxheim « Obere Reben » (Haut-Rhin)"

F. Médard, H. Barrand-Emam, A. Charrié-Duhaut, C. Ridacker, T. Fischbach, Revue Archéologique de l'Est, 2018, 67, 335-349


"CASKA – Navires et navigation en Dalmatie romaine : recherches d’archéologie maritime et navale à Caska (île de Pag, Croatie). Rapport des opérations 2012; Centre Camille Jullian, Université de Zadar: 2012"

G. Boetto, K. Baika, E. Bukowiecki, C. Cenzon-Salvayre, A. Charrié-Duhaut, D. Christodoulou, L. Delavault, V. Dumas, M. Geraga, P. Groscaux, S. Kordella, F. Guibal, G. Papatheodorou, M. Tiller


"Intact monoclonal antibodies separation and analysis by sheathless capillary electrophoresis-mass spectrometry"

J. Giorgetti, A. Lechner, E. Del Nero, A. Beck, YN. Francois, E. Leize-Wagner, European Journal of Mass Spectrometry, 2018, 25,324-332 (pdf)


"Entwined dimer formation from self-complementary bis-acridiniums"
H-P. Jacquot de Rouville, N. Zorn, E. Leize-Wagner, V. Heitz, Chemical Communication, 2018, 54, 10966-10969 (pdf)

 

"High-resolution separation of monoclonal antibodies mixtures and their charge variants by an alternative and generic CZE method"

A. Goyon, YN François, O. Colas, A. Beck, JL Veuthey, D. Guillarme, Electrophoresis, 2018, 39, 2083-2090 (pdf)


Book Chapter "Biopharmaceutical applications of capillary electromigration methods" in Capillary Electromigration Separation Methods

R. Gahoual, J. Giorgetti, A. Beck, E. Leize-Wagner, YN François, edited by Colin Poole, Elsevier, 2018 (pdf, pdf)


"Monoclonal Antibody N-Glycosylation Profiling using Capillary Electrophoresis – Mass Spectrometry: Assessment and Method Validation"

J. Giorgetti, V. D'Atri, J. Canonge, A. Lechner, D. Guillarme, O. Colas, E. Wagner-Rousset, A. Beck, E. Leize-Wagner, YN. François, Talanta, 2018, 178, 530-537 (pdf)


"High-order structural characterization of 10 monoclonal antibodies by combination of intact, middle-up and bottom-up techniques using sheathless capillary electrophoresis-mass spectrometry"

J. Giorgetti, N. Said, R. Gahoual, A. Beck, E. Leize-Wagner, YN. François, Proceedings of the 66th ASMS Conference on Mass Spectrometry and Allied Topics, 2018.


2017

"Can Hemoglobin characteristics of vesicomid clam species influence their ditribution in deep-sea sulfide-rich sediments? A case study in the Angola Basin"

C. Decker, N. Zorn, J. Le Bruhec, J.C. Caprais, N.Potier, E. Leize-Wagner, F.H. Lallier, K. Olu, A.C. Andersen, Deep-Sea Resarch II, 2017, 142, 219-232


"Omics for Precious Rare Biosamples: Characterization of Ancient Human Hair by a Proteomic Approach"

M. Fresnais, P. Richardin, M. Sepulveda, E. Leize-Wagner, A. Charrié-Duhaut, OMICS: a Journal of Integrative Biology, 2017, 21(7), 361-370. (pdf)


"Top-down and middle-down approach by fraction collection enrichment using Off-line CE-UV/MALDI-MS: application to monoclonal antibody Fc/2 charge variants"

M. Biacchi, N. Said, A. Beck, E. Leize-Wagner, YN. François, Journal of Chromatography A, 2017, 1498, 120-127. (pdf)

Audioslide presentation


"Advanced antibody-drug conjugate structural characterization by sheathless capillary electrophoresis-tandem mass spectrometry using complementary approaches"

N. Said, J. Giorgetti, L. Kuhn, A. Beck, E. Leize-Wagner, R. Gahoual, YN. François, LCGC North America, 2017, 15, 15-21 (pdf)


2016

"Cutting-edge capillary electrophoresis characterization of monoclonal antibodies and related products"

R. Gahoual, A. Beck, E. Leize-Wagner, YN. François, Journal of Chromatography B, 2016, 1032, 61-78 (pdf)


"Structural characterization of antibody drug conjugate by a combination of intact, middle-up and bottom-up techniques using sheathless capillary electrophoresis – tandem mass spectrometry as nanoESI infusion platform and separation method"

N. Said, R. Gahoual, L. Kuhn, A. Beck, YN. François, E. Leize-Wagner, Analytica Chimica Acta, 2016, 918, 50-59 (pdf)

Audioslide presentation


"Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Level"

ML. Lepage, JP. Schneider, A. Bodlenner, A. Meli, F. De Riccardis,  M. Schmitt, C. Tarnus, NT. Nguyen-Huynh, YN. Francois, E. Leize-Wagner, C. Birck, A. Cousido-Siah, A. Podjarny, I. Izzo, P. Compain, European-A European Journal, 2016, 22, 5151-5155 (pdf)


"Characterization of Cetuximab Fc/2 subunits aggregates by Off-line CZE-MS"

Y.-N. Francois, M. Biacchi, N. Said, C. Renard, A. Beck, R. Gahoual, E. Leize-Wagner, Analytica Chimica Acta, 2016, 908, 168-176 (pdf)

Audioslide presentation

 

"Improvement of mitochondria extract from Saccharomyces cerevisiae characterization in shotgun proteomic using sheathless capillary electrophoresis coupled to tandem mass spectrometry"

M. Ibrahim, R. Gahoual, L. Enkler, H. Becker, J. Chicher, P. Hammann, Y.-N. Francois, L. Kuhn, E. Leize-Wagner, Journal of Chromatographic Science, 2016, 54(4), 653-663 (pdf)

 

"Monitoring of the Retinoic Acid Receptor - Retinoid X Receptor dimerization upon DNA binding by native mass spectrometry"

N.-T. Nguyen-Huynh, J. Osz, C. Peluso-Iltis, N. Rochel, N. Potier, E. Leize-Wagner, Biophysical Chemistry, 2016, 210, 2-8

 

"Innovative Characterization of Hair from pre-Hispanic Andean Mummies using Mass spectrometry""

M. Fresnais, P. Richardin, M. Sepulveda, E. Leize-Wagner, A. Charrié-Duhaut, Proceedings of the 64th ASMS Conference on Mass Spectrometry and Allied Topics, 2016.

 

"Glycoform Separation and Characterization of Cetuximab Variants by Middle-up Off-line CE-UV/ESI-MS"

N. Said, M. Biacchi, R. Gahoual, C. Renard, A. Beck, Y.-N. Francois, E. Leize-Wagner, Proceedings of the 64th ASMS Conference on Mass Spectrometry and Allied Topics, 2016.

 

"High-order Structural Interrogation of Antibody-drug Conjugates by a Combination of Intact, Middle-up and Bottom-up techniques using Sheathless Capillary Electrophoresis-Msas Spectrometry"

N. Said, R. Gahoual, L. Kuhn, A. Beck, Y.-N. Francois, E. Leize-Wagner, Proceedings of the 64th ASMS Conference on Mass Spectrometry and Allied Topics, 2016.

 

"La spectrométrie de masse, une technique de choix pour l'analyse moléculaire de baumes de momies"

A. Charrié-Duhaut, J. Hertzog, Spectra Analyse, 2016, 312, 54-60

 

"L'apport de l'analyse protéomique à l'étude des cheveux de momies"

Margaux Fresnais, A. Charrié-Duhaut, Spectra Analyse, 2016, 312, 61-69


"Caractérisation fine de protéines thérapeutiques à l’aide du couplage de l’électrophorèse capillaire et de la spectrométrie de masse"

R. Gahoual, M. Biacchi, N. Said, A. Beck, E. Leize-Wagner, YN. Francois, Spectra Analyse, 2016, 311, 52-59 (pdf)


2015

"Independent highly sensivite characterization of asparagine deamidation and aspartic acid isomerization by sheathless CZE-ESI-MS/MS"

R. Gahoual, A. Beck, Y.-N. Francois, E. Leize-Wagner, Journal of Mass Spectrometry, 2015, 51(2), 150-158 (pdf)

 

"Comprehensive Multilevel Characterization of Biologics Usinig Sheathless Capillary Electrophoresis Hyphenated to Tandem Mass Spectrometry"

R. Gahoual, M. Biacchi, JM. Busnel, A. Beck, Y-N. Francois, E. Leize-Wagner, LCGC North America, 2015, 13 (4), 8-15 (pdf)


"Priming the Cells for Their Final Destination: Microenvironment Controlled Cell Culture by a modular ECM-mimicking Feeder Film" (pdf)

J. Barthes, E. Vrana, H. Ozcelik, R. Gahoual, Y. Francois, J. Bacharouche, G. Francius, J. Hemmerlé, M-H. Metz-Boutigue, P. Schaaf, P. Lavalle, Biomaterials Science, 2015, 3, 1302-1311

 

"Glycoform Separation and Characterization of Cetuximab Variants by Middle-up Off-Line Capillary Zone Electrophoresis-UV/Electrospray Ionisation-MS"

M. Biacchi, R. Gahoual, N. Said, A. Beck, E. Leize-Wagner, Y.-N. Francois, Analytical Chemistry, 2015, 87, 6240-6250 (pdf)


"Chemical cross-linking and mass spectrometry to determine the subunit interaction network in a recombinant juman SAGA HAT subcomplex"

N.-T. Nguyen-Huynh, G. Sharov, C. Potel, P. Fichter, S. Trowitzsch, I. Berger, V. Lamour, P. Schultz, N. Potier, E. Leize-Wagner, Protein Science, 2015, 8, 1232-1246

 

"Recent advances in the characterization of hair of mummies from the Chilean Andean coast"

M. Fresnais, P. Richardin, A. Gimat, M. Sepulveda, E. Leize-Wagner, A. Charrié, Forensic Science International, 2015, 249, 25-34

 

"Chemical cross-linking and mass spectrometry to determine the interation network of protein complexes"

N.-T. Nguyen-Huynh, G. Sharov, C. Potel, P. Fichter, S. Trowitzsch, I. Berger, V. Lamour, P. Schultz, N. Potier, E. Leize-Wagne, Proceedings of the 63rd ASMS Conference on Mass Spectrometry and Allied Topics, 2015.

2014

"O12: Analysis of Chilean mummies hair: Recent advance in their characterization"

M. Fresnais, P. Richardin, A. Charrié, M. Sepulveda, E. Leize-Wagner, Toxicologie Analytique et Clinique, Proceedings of the Analytical, Clinical and Forensic Toxicology International Meeting, 2014, 26, S9-S10


"Novel sheathless CE-MS interface as an original and powerful infusion platform for nanoESI study: from intact proteins to high molecular mass noncovalent complexes"

R. Gahoual, J-M. Busnel, P. Wolff, Y-N. François, E. Leize-Wagner, Analytical and Bioanalytical Chemistry, 2014, 406, 1029-1038 (pdf)

 

“Full antibody primary structure and micro-variant characterization in a single injection using transient isotachophoresis and sheath-less capillary electrophoresis – tandem mass spectrometry”

R. Gahoual, J-M. Busnel, A. Beck, Y-N. François, E. Leize-Wagner, Analytical Chemistry, 2014, 86 (18):9074-9081 (pdf)

 

"Globin's Structure and Function in Vesicomyid Bivalves from the Gulf of Guinea Cold Seeps as an Adaptation to Life in Reduced Sediments"

C. Decker, N. Zorn, N. Potier, E. Leize-Wagner, F.H. Lallier, K. Olu, A.C. Andersen, Physiological and Biochemical Zoologyl, 2014, 87 (6):855-869

 

« Analysis of monoclonal antibody by a novel CE-UV/MALDI-MS interface »

M. Biacchi, R. Bhajun, N. Saïd, Y-N. François, E.Leize-Wagner, Electrophoresis, 2014, 20, 2986-2995 (pdf)

 

“Monoclonal antibodies biosimilarity assessment using transient isotachophoresis capillary zone electrophoresis-tandem mass spectrometry”

R. Gahoual, M. Biacchi, J. Chicher, L. Kuhn, P. Hammann, A. Beck, E. Leize-Wagner, Y-N. François, mAbs, 2014, 6 (6), 1464-1473 (pdf)

 

"Intact protein separation by CE-UV/MALDI-MS for top-down proteomics"

M. Biacchi, A. Beck, Y-N. Francois, E. Leize-Wagner, Proceedings of the 62th ASMS Conference on Mass Spectrometry and Allied Topics, 2014.

 

"Monoclonal antibodies complete primary structure and biosimilarity assessment in a single analysis using transient isotachophoresis sheathless capillary electrophoresis-tandem mass spectrometry"

R. Gahoual, J-M. Busnel, J. Chicher, L. Kuhn, P. Hammann, A. Beck, Y-N. Francois, E. Leize-Wagner, Proceedings of the 62th ASMS Conference on Mass Spectrometry and Allied Topics, 2014.

2013

"Structural insight into negative DNA supercoiling by DNA gyrase, a bacterial type 2A DNA topoisomerase"

J. Papillon, J-F. Ménétret, C. Batisse, R. Hélye, P. Schultz, N. Potier, V.Lamour, Nucleic Acids Research, 2013, vol. 41, issue 16, p.7815-7827


"Rapid and multi-level characterization of trastuzumab using sheathless capillary electrophoresis-tandem mass spectrometry"

R. Gahoual,A. Burr, J-M. Busnel, L. Kuhn, P. Hammann, A. Beck, Y-N. François, E. Leize-Wagner, mAbs, 2013, vol. 5, p.479-490 (pdf)

 

"Novel family members of CYP109 from Sorangium cellulosum So ce56 exhibit characteristic biochemical and biophysical properties"

Y. Khatri, F. Hannemann, M. Girhard, R. Kappl, A. Même, M. Ringle, S. Janoche, E. Leize-Wagner, V.B. Urlacher, R. Bernhardt, Biothechnology and Applied Biochemistry, 2013, vol.60, issue 1, p.18-29

 

"The asymmetric binding of PGC-1a to the ERRa and ERRy nuclear receptor homodimers involves a similar recognition mechanism"

M. Takacs, M.V. Petovkhov, R.A. Atkinson, P. Roblin, F-X. Ogi, B. Demeler, N. Potier, Y. Chebaro, A. Dejaegere, D.I. Svergun, I.M.L. Billas, PLOS One, 2013, vol. 8, issue 7, p.1-11

 

"Molecular evidence of bitumen in the Mousterian lithic assemblage of Hummal (Central Syria)"

T.C. Hauck, J. Connan, A. Charrié-Duhaut, J-M. Le Tensorer, H. al Sakhel,  Journal of Archaeological Science, 2013, vol. 40, issue 8, 3252-3262

 

"First molecular identification of a hafting adhesive in the Late Howiesons Poort at Diepkloof Rock Shelter (Western Cape, South Africa)"

A. Charrié-Duhaut, G. Porraz, C.R. Cartwright, M. Igreja, J. Connan, C. Poggenpoel, P-J. Texier, Journal of Archaeological Science, 2013, vol.40, issue 9, 3506-3518

 

"The MSA sequence of Diepkloof and the history of southern African Late Pleistocene populations" 

G. Porraz, J.E. Parkington, J-P. Rigaud, C.E. Miller, C. Poggenpoel, C. Tribolo, W. Archer, C.R. Cartwright, A. Charrié-Duhaut, L. Dayet, M. Igreja, N. Mercier, P. Schmidt, C. Verna, P-J. Texier, Journal of Archaeological Science, 2013, vol. 40, issue 9, 3542-3552

 

"Simultaneous peptide mapping, posttranslational modifications and major N-glycosylation characterization of trastuzumab by sheathless CE-ESI-MS/MS - Comparison to nanoLC-MS/MS"

R. Gahoual, A. Burr, J-M. Busnel, L. Kuhn, P. Hammann, A. Beck, Y-N. François, E. Leize-Wagner, Proceedings of the 61th ASMS Conference on Mass Spectrometry and Allied Topics, 2013.

 

"CE-UV/MALDI-MS: a new platform for proteomic and intact protein characterization"

M. Biacchi, A. Resemann, P-O. Schmit, A. Beck,Y-N. François, E. Leize-Wagner, Proceedings of the 61th ASMS Conference on Mass Spectrometry and Allied Topics, 2013.

2012

"A novel MALDI-MS approach for the analysis of neutral metallosupramolecular architectures"

A. Même, A.R. Stefankiewicz, J. Harrowfield, X-Y. Cao, J. Huuskonen, K. Rissanen, J-M. Lehn, H. Nierengarten, E. Leize, European Journal of Inorganic Chemistry, 2012, 4, 647-654

 

"Biomarqueurs et GC/MS: des principes clés pour la caractérisation, la conservation et la restauration des objets du patrimoine. Applicaton à un adhésif végétal néolithique."

A. Charrié, C. Leprovost, Spectra Analyse, 2012, 825, 32-39

 

"Sheathless Capillary Electrophoresis as an Infusion Platform for the NanoESI Study of Intact Proteins and Non-Covalent Complexes"

R. Gahoual ; Y-N. Francois, E. Leize-Wagner,Proceedings of the 60th ASMS Conference on Mass Spectrometry and Allied Topics, 2012.

 

"Enrichment by fraction collection developed for CE/MALDI-MS to analyze proteins by Top Down strategy"

M. Biacchi, R. Bhajun, Y.N. François, E. Leize-Wagner, Proceedings of the 60th ASMS Conference on Mass Spectrometry and Allied Topics, 2012

2010

"Structural characterization of hemoglobins from Monilifera and Frenulata tube worms (Siboglinids): First discovery of giant hexagonal-bilayer hemoglobin in the former "Pogonophora" group"

C. Meunier, AC Andersen, M. Bruneaux, D. Le Guen, P. Terrier, E. Leize-Wagner, F. Zal, Comp Biochem Physiol A Mol Integr Physiol., 2010, Part A 155, 41-48.



"Insights into metazoan evolution from alvinella pompejana cDNAs"

N. Gagnière, D. Jollivet, I. Boutet, Y. Brévilet, D. Busso, C. Da Silva, F. Gaill, D. Higuet, S. Hourdez, B. Knoops, F. Lallier, E. Leize-Wagner, J. Mary, D. Moras, E. Perrodou, JF. Rees, B. Segurens, B. Shillito, A. Tanguy, JC. Thierry, J. Weissenbach, P. Wincker, F. Zal,O. Poch, O. Lecompte, BMC Genomics, 2010, 11, 634.



"The "Phantom Effect" of the rexinoid LG100754: structural and functional insights"

Y. Sato, N. Ramalanjanoa, T. Huet, N. Potier, J. Osz, P. Antony, C. Peluso-Iltis, P. Poussin-Courtemagne, E. Ennifar, Y. Mély, A. Dejaere, D. Moras, N. Rochel, PLoS One (2010) Nov 30 :5(11) :e15119

2009

"Mass spectrometry contribution for stability constants measurement of protein/protein complexes"

A. Même, P. Terrier, F. Hannemann, R. Bernhardt, H. Nierengarten, N. Potier, E. Leize-Wagner, Proceedings of the 57th ASMS Conference on Mass Spectrometry and Allied Topics, 2009.



"Power and limitations of electrophoretic separations in proteomics strategies"

T. Rabilloud, AR. Vaezzadeh, N. Potier, C. Lelong, E. Leize-Wagner, M. Chevallet, Mass Spectrom Rev., 2009, 28, 816-43.



"Structural study of Carcinus maenas hemocyanin by native ESI-MS: interaction with L-lactate and divalent cations"

M. Bruneaux, P. Terrier, E. Leize, J. Mary, FH. Lallier, F. Zal, Proteins, 2009, 77, 589-601.



"A novel generic and effective method for the rapid purification of G-protein-coupled receptors"

T. Magnin, C. Fiez-Vandal, N. Potier, A. Coquard, I. Leray, T. Steffan, C. Logez, F. Alkhalfioui, F. Pattus, R. Wagner, Protein Exp. Purif., 2009, 64, 1-7.



"Crystal growth of proteins, nucleic acids and viruses in gels"

B. Lorber, C. Sauter, A. Théobald-Dietrich, A. Moreno, P. Schellenberger, MC. Robert, B. Capelle, S. Sanglier, N. Potier, R. Giegé, Prog Biophys Mol Biol. 2009, 101 (1-3), 13-25

2008

"Aldosterone: from biosynthesis to non-genomic action on the proteome"

S. Zöllner, KH. Hwang, B. Wilzewski, C. Carapito, E. Leize-Wagner, A. Van Dorsselaer, R. Bernhardt, Steroids, 2008, 73, 966-72.



"Respiratory adaptations of a deep-sea hydrothermal crustacean: The case of Segonzacia mesatlantica"

M. Bruneaux, J. Pasquier, P. Terrier, E. Leize, F. Lallier, F. Zal, Comparativ Biochemistry and Physiology - Part A: Molecular& Integrative Physiology, 150, 2008, S119.

2007

"Ruthenium(II) complexes with improved photophysical properties based on planar 4'-(2-Pyrimidinyl)-2,2' :6,2''-terpyridine ligands"

Y.Q. Fang, N.J. Taylors, F. Laverdiere, G.S. Hanan, F. Loiseau, F. Nastasi, S. Campagna, H. Nierengarten, E. Leize-Wagner, A. Van Dorsselaer, Inorg. Chem., 2007, 46 2854-2863.



"A tale of two oxidation states : Bacterial colonization of arsenic-rich environments"

D. Muller, c. Medigue, S. Koechler, V. Barbe, M. Barakat, E. Talle, V. Bonnefroy, E. Krin, F. Arsene-Ploetze, C. Carapito, M. Chandler, B. Cournoyer, S. Cruveiller, C. Dossat, M. Heymann, E. Leize, A. Lieutaud, D. Lievremont, Y. Makita, S. Mangenot, W. Nitschke, P. Ortet, N. Perdrail, B. Schoepp, P. Siguier, DD. Simeonova, Z. Rouy, B. Segurens, E. Turlin, D. Vallenet, A. Van Dorsselaer, S. Weiss, J. Weissenbach, MC. Lett, A. Danchin, PN. Bertin, Plos Genetics, 2007, 3.



"Short term adaptive, response and phenotypic plasticity of Crustacean hemocyanins : Study of Carcinus maenas and Segonzacia mesatlantica"

M. Bruneaux, F. Zal, E. Leize, Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology, 2007, 146, S85-S86



"Macrotricycles featuring a pi-basic tetrahedral cavity : preference for NH4+ detected by ESI-MS"

A. Lelias-Vanderperre, JC. Chambron, E. Espinosa, P. Terrier, E. Leize-Wagner, Organic Letters, 2007, 9, 2961-2964.



"The structural analysis of large noncovalent oxygen binding proteins by MALLS and ESI-MS: previous works and new insights concerning annelid hexagonal bilayer hemoglobin and crustacean hemocyanin"

M. Bruneaux, M. Rousselot, E. Leize, FH. Lallier, F. Zal, Current Protein and Peptide Science, 2007, 2008, 9, 15-80.



"Supramolecular circular helicates formed by destabilisation of supramolecular dimers"

J. Hamblin, F. Tuna, S. Bunce, LJ Childs, A. Jackson, W. Errington, NM. Alcock, H. Nierengarten, A. Van Dorsselaer, E. Leize-Wagner, MJ Hannon, Chemistry, 2007, 13, 9286-96.



"Lanthanide complexation with CMPO and CMPO-calix[4]arenes in solution: spectrophotometric and electrospray mass spectrometric approaches"

H. Herschbach, F. Brisach, J. Haddaoui, M. Saadioui, E. Leize, A. Van Dorsselaer, F. Arnaud-Neu, V. Böhmer, Talanta, 2007, 74, 39-46.



"Determination of aqueous inclusion complexation constants ans stoichiometry of alkyl(methyl)-methylimidazolium-based ionic liquid cations and neutral cyclodextrins by affinity capillary electrophoresis"

Y. François, A. Varenne, J. Sirieix-Plenet, P. Gareil, Journal of Separation Science, 2007, Volulme 30, Issues 5, Pages 751-760. (pdf)



"Nonaqueous capillary electrophoretic behavior of 2-aryl propionic acids in the presence of an achiral ionic liquid : A chemometric approach"

Y. François, A. Varenne, E. Juillerat, A-C. Servais, P. Chiap, P. Gareil, Journal of Chromatography A, 1138, (1-2), 2007, Pages 268-275. (pdf)



"Evaluaton of chiral ionic liquids as additives to cyclodextrins for enantiomeric separations by capillary electrophoresis"

Y. François, A. Varenne, E. Juillerat, D. Villemin, P. Gareil, Journal of Chromatography A, Volume 1155, Issue 2, 2007, Pages 134-141. (pdf)

2006

"Alterations of the mitochondrial proteome caused by the absence of mitochondrial DNA : a proteomic view"

M. Chevalet, P. Lescuyer, H. Diemer, A. Van Dorsselaer, E. Leize-Wagner, T. Rabilloud, Electrophoresis, 2006, 27, 1574-1583.



"Preparation of alumina supported gold catalysts : gold complexes genesis, identification and speciation by mass spectrometry"

S. Ivanova, V. Pichon, C. Petit, H. Herschbach, A. Van Dorsselaer, E. Leize, Applied Catalysis, 2006, 298, 203-210.



"Oxidative stess response : a proteomic view"

T. Rabilloud, M. Chevallet, S. Luche, E. Leize-Wagner, Expert Review of Proteomics, 2005, 2, 949-956.



"Analysis of aldosterone-induced differential receptor-independent protein patterns using 2D-electrophoresis and mass spectrometry"

S. Bohmer, C. Carapito, B. Wilzewski, E. Leize, A. Van Dorsselaer, R. Bernhardt, Biol Chem., 2006, 387, 917-929.



"Electrospray mass spectrometry analysis of dendritic branches bearing peripheral fullerene subunits"

H. Herschbach, K. Hosomizu, U. Hahn, E. Leize, A. Van Dorsselaer, H. Imahori, JF. Nierengarten, Anal Bioanal Chem., 2006, 386, 46-51.



"Proteome analysis of Schizosaccharomyces pombe by two-dimensional gel electrophoresis and mass spectrometry"

K. Hwang, C. Carapito, S. Bohmer, E. Leize, A. Van Dorsselaer, R. Bernhardt, Proteomics, 2006, 6, 4115-4129.



"Synthesis of fullerodendrons with an ammonium unit at the focal point and their cooperative self-assembly on a fluorescent ditopic crown ether receptor"

JF. Nierengarten, U. Hahn, A. Trabolsi, H. Herschbach, F. Cardinali, M. Elhabiri, E. Leize; A. Van Dorsselaer, AM. Albrecht-Gary, Chemistry, 2006, 12, 3365-3373.



"Improved mass spectrometry compatibility is afforded by ammoniacal silver staining"

M. Chevalet, H. Diemer, S. Luche; A. Van Dorsselaer, T. Rabilloud, E. Leize-Wagner, Proteomics, 2006, 6, 2350-2354.



"New integrated measurement protocol using capillary electrophoresis instrumentation for the determination of viscosity, conductivity and absorbance of ionic liquid-molecular solvent mixtures"

Y. François, K. Zhang, A. Varenne, P. Gareil, Analytica Chimica Acta, Volume 562, Issue 2, 2006, Pages 164-170. (pdf)